Clinical Research-old
Clinical Efficacy
Proven Clinical Results – Unique Study Design
- Fully blinded with sham device (Placebo) as control arm
- Eliminated Placebo Effect – Patients and Clinicians did not know treatment arm
- Highest Level of Clinical Evidence – Level 1A (Double Blind with Placebo)
Statistically Significant Outcomes in 12 Weeks
- CDO leads to significantly higher rates of closure (2x to 3x)
- CDO works better in more chronic wounds (lower PWAR*)
- CDO resulted in significantly faster time to closure (P<0.001)
How Oxygen Works In Wound Healing
Increases Cell Metabolism & Energy
Continuous Pure Oxygen boosts vitality
7
Enhances Bodies Own Anti-Bacterial Capacity
Create Reactive Oxygen Species (i.e. Hydrogen Peroxide)
5,6
Greater Wound Perfusion
Rate of angiogenesis proportional to oxygen concentration
8,9
Better Strength & Appearance
- Higher tensile strength (reduced recurrence) 10,11
- Better collagen organization (reduced scarring) 12
Faster Cell Growth & Re-epithelialization
- Increased collagen deposition (faster repair) 11,13,14
- Up to 70% faster endothelial gap closure rate 12
Read More about how oxygen works in wound healing
Publications
Recommendations
Wound Healing Society DFU Treatment Guidelines Recommended topical oxygen as a Level 1 treatment recommendation “Topical oxygen has been shown…
Guidelines for the use of topical oxygen therapy in the treatment of hard-to-heal wounds based on a Delphi consensus – Summary
Download Summary PDF Read Article on JWC
Case Studies
Outcome: Wound Closed
Days on Service: 47
Outcome: Wound Healed
Days on Service: 81
Outcome: Wound healed
Days on Service: 55
Outcome: 99% Closure
Days on Service: 93
EO2 Concepts® is an ISO 13485:2016 certified company that maintains European Commission CE mark certification and obtained its Canadian Medical Device License for distribution of innovative wound care products throughout the United States, Canada and the European Union.
