Level of Evidence	Author (s)	Study	Year Published	Publication Site	Wound Type	Citation
4a	Kimmel HM	A Comparison of Continuous Oxygen Therapy to Topical Oxygen	2019	Foot & Ankle Quarterly	various	Kimmel HM, A Comparison of Continuous Oxygen Therapy to Topical Oxygen, Foot & Ankle Quarterly, Winter 2019, 30(4) 203-209
1a	Lavery LA, Niederauer MQ, Papas KK, Armstrong DG	Does Debridement Improve Clinical Outcoes in People with DFU Ulcers Treated with CDO?	2019	Wounds	DFU	Lavery LA, Niederauer MQ, Papas KK, Armstrong DG, Does Debridement Improve Clinical Outcomes in People with DFU Ulcers Treated with CDO? Wounds 31(10):246-251 2019. Epub 2019 July 31.
1a	Niederauer MQ, Michalek JE, Liu Q, Papas, Lavery LA, Armstrong DG	Continuous Diffusion of Oxygen Improves Diabetic Foot Ulcer Healing When Compared with a Placebo Control: a Randomised, double-blind, multicentre study	2018	Journal Wound Care	DFU	Niederauer MQ, Michalek JE, Liu Q, Papas, Lavery LA, Armstrong DG. Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control: a randomised, double-blind, multicentre study. J Wound Care 27(9):s30-s45 2018.
2a	Bowen J, Ingersoll MS, Carlson R	Effect of CDO on Pain in Treatment of Chronic Wounds	2018	Wound Central	Chronic wounds	Bowen J, Ingersoll MS, Carlson R. Effect of CDO on Pain in Treatment of Chronic Wounds. Wound Central 2(4);186-195 2018.
1a	Niederauer MQ, Michalek JE, Armstrong DG	A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen Therapy to Sham Therapy in the Treatment of Diabetic Foot Ulcers	2017	Journal Diabetes Science Technology	DFU	Niederauer MQ, Michalek JE, Armstrong DG. A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen Therapy to Sham Therapy in the Treatment of Diabetic Foot Ulcers. J Diabetes Science Tech. 2017, Special Issue, 1-9. DOI: 1h0t.t1p1s:7//7d/o1i.9o3rg2/1209.6118717/1693525279468
1a	Niederauer MQ, Michalek JE, Armstrong DG	Interim Results for a Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen Therapy to Standard Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers.	2015	Wound Medicine	DFU	Niederauer MQ, Michalek JE, Armstrong DG. Interim Results for a Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen Therapy to Standard Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers. Wound Medicine 8:19-23, 2015.
2a	Couture M	Does Continuous Diffusion of Oxygen Have Potential in Chronic Diabetic Foot Ulcers?	2015	Podiatry Today	Chronic DFU	Couture M. Does Continuous Diffusion Of Oxygen Have Potential In Chronic Diabetic Foot Ulcers? Podiatry Today 28(12) 2015.
2a	Urrea-Botero G	Can Continuous Diffusion of Oxygen Heal Chronic Toe Ulcers?	2015	Podiatry Today	Chronic Toe Ulcers	Urrea-Botero G. Can Continuous Diffusion of Oxygen Heal Chronic Toe Ulcers? Podiatry Today 28(10) 2015.
3b	Brannick B, Engelthaler M, Jadzak J, Wu S	A Closer Look at Continuous Diffusion of Oxygen Therapy for a Chronic, Painful Venous Leg Ulcer	2014	Podiatry Today	Chronic, Painful VLU	Brannick B, Engelthaler M, Jadzak J, Wu S. A Closer Look at Continuous Diffusion of Oxygen Therapy for a Chronic, Painful Venous Leg Ulcer. Podiatry Today 27(11) 2014.
4a	Howard MA, Asmis R, Evans KK, Mustoe TA	Oxygen and wound care- A review of current therapeutic modalities and future direction	2013	Wound Repair and Regeneration	various	Howard MA, Asmis R, Evans KK, Mustoe TA. Oxygen and wound care- A review of current therapeutic modalities and future direction. Wound Rep Reg. 2013; 21(4):503-511.
4b	Asmis R, Qiao M, Zhao Q	Low-Flow Oxygenation of Full-Excisional Skin Wounds on Diabetic Mice Improves Wound Healing by Accelerating Wound Closure and Reepithelialization	2010	International Wound Journal	animal study	Asmis R, Qiao M, Zhao Q. Low-Flow Oxygenation of Full-Excisional Skin Wounds on Diabetic Mice Improves Wound Healing by Accelerating Wound Closure and Reepithelialization. Int Wound J 2010 ; 7: 349-357.